Alcoholism: the role of different motivational systems.

  title={Alcoholism: the role of different motivational systems.},
  author={Robert O. Pihl and J. B. Peterson},
  journal={Journal of psychiatry & neuroscience : JPN},
  volume={20 5},
Individuals use and misuse alcohol (and other drugs) because of the pharmacologically mediated effects these substances have on the operation of 4 psychobiological systems, mediating response to motivationally relevant unconditioned and conditioned stimuli. These 4 systems have unique neuroanatomical structure, biochemical modes of operation, association with affect, behavior and cognition, and responsiveness to drugs of abuse. Individual variation in the operation of these systems determines… CONTINUE READING