Alcohol withdrawal seizures

  title={Alcohol withdrawal seizures},
  author={J. R. Hughes},
  journal={Epilepsy & Behavior},
  • J. R. Hughes
  • Published 2009
  • Medicine
  • Epilepsy & Behavior
  • The topic of alcohol withdrawal syndrome (AWS), including delirium tremens and especially seizures, is reviewed. From mice and rat studies, it is known that both N-methyl-d-aspartate (NMDA) and gamma-aminobutyric acid (GABA) receptors are involved in AWS. During alcohol intoxication chronic adaptations of NMDA and GABA receptors occur, and during alcohol withdrawal a hyperexcitable state develops. In studies on humans, during intoxication the NMDA receptors are activated and mediate tonic… CONTINUE READING
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    Acute withdrawal: diagnosis and treatment.
    • J. Brust
    • Medicine
    • Handbook of clinical neurology
    • 2014
    • 17
    Neurobiological alterations in alcohol addiction: a review.
    • 21
    • PDF
    Susceptibility to ethanol withdrawal seizures is produced by BK channel gene expression
    • 43
    Activity of hippocampal adult-born neurons regulates alcohol withdrawal seizures.
    • 1
    • PDF


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    • 59
    • PDF
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    • 141
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    • 80
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    • 12
    Alcoholism-related phenotypes and genetic variants of the CB1 receptor
    • 40
    An ethanol protocol to prevent alcohol withdrawal syndrome.
    • 39
    Role of the amygdala in ethanol withdrawal seizures
    • 17
    Polymorphisms in the NMDA subunit 2B are not associated with alcohol dependence and alcohol withdrawal–induced seizures and delirium tremens
    • 24
    Lorazepam and MK-801 effects on behavioral and electrographic indices of alcohol withdrawal sensitization
    • 25
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