Alcohol withdrawal seizures

@article{Hughes2009AlcoholWS,
  title={Alcohol withdrawal seizures},
  author={J. R. Hughes},
  journal={Epilepsy & Behavior},
  year={2009},
  volume={15},
  pages={92-97}
}
  • J. R. Hughes
  • Published 2009
  • Medicine
  • Epilepsy & Behavior
    • The topic of alcohol withdrawal syndrome (AWS), including delirium tremens and especially seizures, is reviewed. From mice and rat studies, it is known that both N-methyl-d-aspartate (NMDA) and gamma-aminobutyric acid (GABA) receptors are involved in AWS. During alcohol intoxication chronic adaptations of NMDA and GABA receptors occur, and during alcohol withdrawal a hyperexcitable state develops. In studies on humans, during intoxication the NMDA receptors are activated and mediate tonic… CONTINUE READING
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