Alcohol withdrawal-induced changes in brain biogenic amines in mice: Influence of the genotype

@article{Kempf1990AlcoholWC,
  title={Alcohol withdrawal-induced changes in brain biogenic amines in mice: Influence of the genotype},
  author={Eliane Kempf and Jules Kempf and Alix Ebel},
  journal={Neurochemical Research},
  year={1990},
  volume={15},
  pages={69-75}
}
Alterations in striatal and hippocampal dopamine (DA) and serotonin (5HT) activities were investigated in two inbred strains of mice (C57B1 and Balb/c) after 3 withdrawal periods following 5 months chronic ethanol administration. Two groups of animals with different levels of ethanol administration (15% and 30%, v/v) were examined. A striking strain dependency has been noted. Striatal dopaminergic mechanisms of the Balb/c strain are profoundly disturbed in both groups. In contrast no changes… CONTINUE READING