Alcohol versus brush PRK: Visual outcomes and adverse effects

@article{Sia2012AlcoholVB,
  title={Alcohol versus brush PRK: Visual outcomes and adverse effects},
  author={Rose K Sia and Denise S. Ryan and Richard D. Stutzman and Maximilian Psolka and Michael J. Mines and Melvin E Wagner and Eric D Weber and Keith J. Wroblewski and Kraig S. Bower},
  journal={Lasers in Surgery and Medicine},
  year={2012},
  volume={44}
}
A smooth corneal surface prior to laser ablation is important in order to achieve a favorable refractive outcome. In this study, we compare PRK outcomes following two commonly used methods of epithelial debridement: Amoils epithelial scrubber (brush) versus 20% ethanol (alcohol). 
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9 Citations
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Methods Citations
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9 Citations

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Citation Type

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References

SHOWING 1-10 OF 20 REFERENCES
A prospective evaluation of alcohol-assisted versus mechanical epithelial removal before photorefractive keratectomy.
Mechanical vs. alcohol epithelial removal during photorefractive keratectomy.
TLDR
Eithelial debridement using a 20% alcohol solution was faster to perform, and provided sharper edges and a smoother Bowman's layer surface than mechanical debridements, which may explain the better results in terms of haze and corneal regularity.
Dilute ethanol versus mechanical debridement before photorefractive keratectomy
Comparison of postoperative pain in patients following photorefractive keratectomy versus advanced surface ablation
Epithelial healing and clinical outcomes in excimer laser photorefractive surgery following three epithelial removal techniques: mechanical, alcohol, and excimer laser.
Corneal haze after photorefractive keratectomy using different epithelial removal techniques: mechanical debridement versus laser scrape.
Evaluation of current techniques of corneal epithelial removal in hyperopic photorefractive keratectomy
Photorefractive keratectomy using a scanning‐slit laser, rotary epithelial brush, and chilled balanced salt solution
Wound healing anomalies after excimer laser photorefractive keratectomy: correlation of clinical outcomes, corneal topography, and confocal microscopy.
  • R. Steinert
  • Medicine
    Transactions of the American Ophthalmological Society
  • 1997
TLDR
Vision and predictability are reduced by anomalies 1 month post-PRK but anomalies often resolve by 6 months, and Marked improvement of vision occurs even when anomalies persist.
Clinical results of excimer laser photorefractive keratectomy: a multicenter study of 265 eyes.
...
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