Alcohol unmasks simian immunodeficiency virus-induced cognitive impairments in rhesus monkeys.

@article{Winsauer2002AlcoholUS,
  title={Alcohol unmasks simian immunodeficiency virus-induced cognitive impairments in rhesus monkeys.},
  author={Peter J. Winsauer and Joseph M. Moerschbaecher and Ian N Brauner and Jeanette E. Purcell and Jack Lancaster and Gregory J. Bagby and Steve Nelson},
  journal={Alcoholism, clinical and experimental research},
  year={2002},
  volume={26 12},
  pages={
          1846-57
        }
}
BACKGROUND Alcohol and human immunodeficiency virus (HIV) produce similar neuropathological profiles, including loss of neurons in the frontal cortex. Additionally, HIV-positive patients with a history of alcohol abuse have greater neurologic deficits, and chronic alcohol abuse produces electrophysiological deficits earlier in the HIV disease process. Few studies, preclinical or clinical, have examined whether alcohol administration exacerbates the neuropsychological deficits in subjects with… CONTINUE READING

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