Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics.

@article{FlatscherBader2005AlcoholresponsiveGI,
  title={Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics.},
  author={Traute Flatscher-Bader and Marcel van der Brug and John W Hwang and Peter Andre Gochee and Izuru Matsumoto and Shin-ichi Niwa and Peter A. Wilce},
  journal={Journal of neurochemistry},
  year={2005},
  volume={93 2},
  pages={
          359-70
        }
}
The molecular processes underlying alcohol dependence are not fully understood. Many characteristic behaviours result from neuroadaptations in the mesocorticolimbic system. In addition, alcoholism is associated with a distinct neuropathology. To elucidate the molecular basis of these features, we compared the RNA expression profile of the nucleus accumbens and prefrontal cortex of human brain from matched individual alcoholic and control cases using cDNA microarrays. Approximately 6% of genes… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 74 CITATIONS

Patterns of Gene Expression in the Frontal Cortex Discriminate Alcoholic from Nonalcoholic Individuals

  • Neuropsychopharmacology
  • 2006
VIEW 4 EXCERPTS
CITES BACKGROUND, METHODS & RESULTS
HIGHLY INFLUENCED

Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice

VIEW 3 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening.

  • Progress in molecular biology and translational science
  • 2011
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2005
2019

CITATION STATISTICS

  • 16 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

Similar Papers

Loading similar papers…