Alcohol promotes mammary tumor growth through activation of VEGF-dependent tumor angiogenesis

@inproceedings{Lu2014AlcoholPM,
  title={Alcohol promotes mammary tumor growth through activation of VEGF-dependent tumor angiogenesis},
  author={Yanmin Lu and Fang Ni and Mei Q Xu and Jinlian Yang and Ji Chen and Zhuo Chen and Xinyi Wang and Jia Luo and Siying Wang},
  booktitle={Oncology letters},
  year={2014}
}
Alcohol consumption has been recognized as a risk factor for breast cancer. Experimental studies demonstrate that alcohol exposure promotes the progression of existing mammary tumors. However, the mechanisms underlying this effect remain unclear. In the present study, the role of vascular endothelial growth factor (VEGF) in alcohol promotion of breast cancer development was investigated using a mouse xenograft model of mammary tumors and a three-dimensional (3D) tumor/endothelial cell co… CONTINUE READING
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