Alcohol metabolism and oesophageal cancer: a systematic review of the evidence.


Alcohol is a major risk factor for oesophageal squamous cell carcinoma (OSCC), the most prevalent histological subtype of oesophageal cancer (OC) worldwide. The metabolism of alcohol is regulated by specific enzymes whose activity and expression is influenced by genetic polymorphisms. We conducted a systematic review of current epidemiological evidence of… (More)
DOI: 10.1093/carcin/bgx067