Alcohol-induced state-dependent learning in non-alcoholics.

@article{Hinrichsen1974AlcoholinducedSL,
  title={Alcohol-induced state-dependent learning in non-alcoholics.},
  author={James J. Hinrichsen and Martin Katahn and Robert W Levenson},
  journal={Pharmacology, biochemistry, and behavior},
  year={1974},
  volume={2 3},
  pages={
          293-6
        }
}
Abstract The generality of the dissociative effects of a high dosage (1.40 g/kg) of rapidly ingested ethyl alcohol in non-alcoholic human subjects was examined. Verbal memory was found to be more susceptible to dissociation than either motor-skills learning or autonomic (heart-rate) control training. The dissociation of the verbal material appeared to be asymmetrical in that subjects who originally learned the material while intoxicated but were tested 48 hr later while sober showed a greater… Expand
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In both studies, intoxication produced a performance deficit, but retention loss on Day 2 was the same for change- and constant-state subjects, and Expectation had no effect on performance. Expand
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It is shown that gaboxadol induces profound changes of local and network oscillatory activity, indicative of discoordinated hippocampal-cortical activity, that were accompanied by robust and long-lasting state-dependent conditioned fear, suggesting that continued dependence on hippocampal rather than cortical mechanisms could be an important feature of state- dependent memories that contributes to their conditional retrieval. Expand
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Recent advances in the neurobiology of memory are highlighted that allow us to isolate and visualize memory circuits, change their activity using genetic tools and state-dependent manipulations, and directly examine their impact on socio-affective circuits and global network connectivity. Expand
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  • J. Eich
  • Psychology, Medicine
  • Memory & cognition
  • 1980
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The message of this article is that the unpredictability of state-dependent effects in man is more apparent than real and failures to demonstrate state dependence are restricted to situations in which utilization of stored information is tested in the presence of discretely identifiable retrieval cues. Expand
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