Alcohol-heightened aggression in mice: attenuation by 5-HT1A receptor agonists

@article{Miczek1998AlcoholheightenedAI,
  title={Alcohol-heightened aggression in mice: attenuation by 5-HT1A receptor agonists},
  author={K. Miczek and Subuhee Hussain and S. Faccidomo},
  journal={Psychopharmacology},
  year={1998},
  volume={139},
  pages={160-168}
}
Abstract One of the critical mechanisms by which alcohol heightens aggression involves forebrain serotonin (5-HT) systems, possibly via actions on 5-HT1A receptors. The present experiments tested the hypothesis that activating 5-HT1A receptors by selective agonists will block the aggression-heightening effects of ethanol. Initially, the selective antagonist WAY 100635 was used to assess whether or not the changes in aggressive behavior after treatment with 8-OH-DPAT and flesinoxan result from… Expand
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