Alcohol dehydrogenases: a family of isozymes with differential functions.

@article{Holmes1994AlcoholDA,
  title={Alcohol dehydrogenases: a family of isozymes with differential functions.},
  author={Roger S. Holmes},
  journal={Alcohol and alcoholism (Oxford, Oxfordshire). Supplement},
  year={1994},
  volume={2},
  pages={127-30}
}
  • Roger S. Holmes
  • Published 1994 in
    Alcohol and alcoholism (Oxford, Oxfordshire…
Human alcohol dehydrogenases (ADHs) are encoded by at least 7 genes, and comprise at least 5 Classes. The isozymes are differentially distributed in tissues, with most Classes exhibiting highest activity in liver. Class IV (mu or sigma) ADH exhibits high activity in stomach and cornea. Class I ADHs have a wide range of physiological substrates, in addition to ethanol, involving metabolism of the following: bile compounds; testosterone; neurotransmitters; congeners; retinol; peroxidic aldehydes… CONTINUE READING
12 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…