Alcohol and hepatocellular carcinoma: the effect of lifetime intake and hepatitis virus infections in men and women.

@article{Donato2002AlcoholAH,
  title={Alcohol and hepatocellular carcinoma: the effect of lifetime intake and hepatitis virus infections in men and women.},
  author={Francesco Di Donato and Alessandro Tagger and Umberto Gelatti and Giovanni Parrinello and Paolo Boffetta and Alberto Albertini and Adriano Decarli and Paola Trevisi and Maria Lisa Ribero and Claudia Martelli and Stefano Porru and Giuseppe Nardi},
  journal={American journal of epidemiology},
  year={2002},
  volume={155 4},
  pages={323-31}
}
The authors investigated the dose-effect relation between alcohol drinking and hepatocellular carcinoma (HCC) in men and women separately, also considering hepatitis B and hepatitis C virus infections. They enrolled 464 subjects (380 men) with a first diagnosis of HCC as cases and 824 subjects (686 men) unaffected by hepatic diseases as controls; all were hospitalized in Brescia, northern Italy, in 1995-2000. Spline regression models showed a steady linear increase in the odds ratio of HCC for… CONTINUE READING
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