Alcohol Use as a Comorbidity and Precipitant of Primary Headache: Review and Meta-analysis

  title={Alcohol Use as a Comorbidity and Precipitant of Primary Headache: Review and Meta-analysis},
  author={Rachel Davis-Martin and Ashley N. Polk and Todd A Smitherman},
  journal={Current Pain and Headache Reports},
Purpose of ReviewIn contrast to well-established relationships between headache and affective disorders, the role of alcohol use in primary headache disorders is less clear. This paper provides a narrative overview of research on alcohol use disorders (AUDs) in primary headache and presents a meta-analysis of the role of alcohol as a trigger (precipitant) of headache.Recent FindingsThe majority of studies on AUDs in headache have failed to find evidence that migraine or tension-type headache… 

Prospective cohort study of daily alcoholic beverage intake as a potential trigger of headaches among adults with episodic migraine

1–2 servings of alcoholic beverages were not associated with higher risk of headaches the following day, but 5+ servings were associated withHigher risk, and higher levels of intake may be associated with high risk.

Clinical characterization of delayed alcohol-induced headache

DAIH is a moderate-intensity headache, is typically bilateral, and presents with frontal predominance and a pressing quality, and the phenotype of DAIH combines features of both migraine and low-CSF-pressure headaches.

Sulfite concentration and the occurrence of headache in young adults: a prospective study

In this group of subjects, sulfite concentration in wine is related to the risk of developing headaches in individuals who are susceptible to wine induced headaches.

Obesity, Weight Loss, and Nutrition in Headache Disorders

An overview of obesity and the evidence supporting its connection to chronic daily headache (CDH) is presented and the impact of weight loss on headache will be reviewed through its association with body mass index.

Red wine triggers may lead to better understanding of migraine headache: a narrative review

The role of sulfotransferase enzymes and dopamine appears to offer a promising explanation of the red wine headache and the investigation of potential red wine triggers may better elucidate headache pathogenesis.

Explaining Disparities in Severe Headache and Migraine Among Sexual Minority Adults in the United States, 2013–2018

  • K. Heslin
  • Psychology, Medicine
    The Journal of nervous and mental disease
  • 2020
Regression decomposition was used to identify determinants of disparities in headache/migraine between sexual minorities collectively and heterosexuals, as well as between bisexual men and gay men, and bisexual women and lesbians.

Cohort profile: COpenhagen ROsacea COhort (COROCO) and COpenhagen MIgraine COhort (COMICO)

These cohorts will help uncover potential disease overlaps and allow for prolonged follow-up through national Danish health registers and serve as strong data sources that will be used for future studies on rosacea and migraine with focus on risk factors, occurrence, treatment, natural history, complications, comorbidities and prognosis.

Alcoholic beverages as trigger factor and the effect on alcohol consumption behavior in patients with migraine

This work aimed to assess self‐reported alcohol consumption as a migraine attack trigger and to investigate the effect on alcohol consumption behavior in a large migraine cohort.



Alcoholic drinks as triggers in primary headaches.

The data suggest that AD do not trigger MA and TH attacks, and occasional and habitual drinkers have a lower risk of presenting with CM than abstainers, although statistical significance occurred only among occasional drinkers.

Alcohol use problems in migraine and tension-type headache.

The results suggest that migraine patients are less prone to alcohol use problems than tension-type headache patients, and one of the possible reasons is that migraine is associated with greater impact than tension -type headache.

Alcohol and migraine: trigger factor, consumption, mechanisms. A review

This study investigates the importance of alcohol as a migraine trigger factor, the prevalence of alcohol consumers and the mechanism of headache provocation, and the discussion based on the different composition of the various alcoholic beverages, in order to discover the content of alcoholic drinks responsible for migraine attack.

Headache prevalence related to smoking and alcohol use. The Head‐HUNT Study

The association between headache and smoking found in the present study raises questions about a causal relationship, e.g. that smoking causes headache or that it allays stress induced by headache, which is probably explained by the headache precipitating properties of alcohol.

Alcohol and Migraine: What Should We Tell Patients?

It is believed that reports overestimate the role of alcohol, as well as other foods, in the triggering of migraine and if a relationship between the intake of alcohol and the migraine attack is not clear, a small dose of alcohol is not contraindicated either for enjoyment or its protective effect on cardiovascular disease.

Impact of comorbidity on headache-related disability

Comorbidity is an important factor in understanding disability among persons with headache and explained 65% of the role disability associated with migraine and all of the roles disability associatedwith other severe headaches.

Crying as a precipitating factor for migraine and tension-type headache.

The act of crying seems to be an important precipitating factor for primary headaches and it should be studied further.