Alcohol Dehydrogenase (ADH) Isoenzymes and Aldehyde Dehydrogenase (ALDH) Activity in the Human Pancreas

@article{Chrostek2003AlcoholD,
  title={Alcohol Dehydrogenase (ADH) Isoenzymes and Aldehyde Dehydrogenase (ALDH) Activity in the Human Pancreas},
  author={Lech Chrostek and Wojciech Jelski and Maciej Szmitkowski and Zbigniew Puchalski},
  journal={Digestive Diseases and Sciences},
  year={2003},
  volume={48},
  pages={1230-1233}
}
Ethanol metabolism in the pancreas occurs predominantly by way of an nonoxidative pathway to fatty acid ethyl esters but oxidative routes to acetaldehyde also may contribute to injury of pancreatic cells. Three metabolic systems are responsible for the oxidative metabolism of ethanol, among which the cytochrome P-4502E1 and alcohol dehydrogenase have been found in the pancreas. The aims of this study were to detect ADH and ALDH in the human pancreas and to assess which ADH isoenzymes are… CONTINUE READING

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