Alcohol Consumption and Cancer Risk

@article{Pelucchi2011AlcoholCA,
  title={Alcohol Consumption and Cancer Risk},
  author={Claudio Pelucchi and Irene Tramacere and Paolo Boffetta and Eva Negri and Carlo La Vecchia},
  journal={Nutrition and Cancer},
  year={2011},
  volume={63},
  pages={983 - 990}
}
This review focuses on selected aspects of the relation between alcohol consumption and cancer risk. Heavy alcohol consumption (i.e., ≥4 drinks/day) is significantly associated with an increased risk of about 5-fold for oral and pharyngeal cancer and esophageal squamous cell carcinoma, 2.5-fold for laryngeal cancer, 50% for colorectal and breast cancers, and 30% for pancreatic cancer. These estimates are based on a large number of epidemiological studies and are generally consistent across… 
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Alcohol and cancer risk, with focus on moderate drinkers
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European Code against Cancer 4th Edition: Alcohol drinking and cancer.
Alcohol and mouth cancer
TLDR
The role for alcohol in the aetiology of mouth cancer both in terms of how it may give rise to cancerous change and the relative risk it carries is reviewed.
European Code against Cancer 4th Edition: Alcohol drinking and cancer.
Consumption of alcohol and risk of cancer among men: a 30 year cohort study in Lithuania
TLDR
No statistically significant associations were found between quantity of alcohol intake per one occasion and risk of cancer in a population-based cohort study of men in Lithuania.
Alcohol, smoking and the risk of premalignant and malignant colorectal neoplasms.
Is there an association between trends in alcohol consumption and cancer mortality? Findings from a multicountry analysis
TLDR
Examination of long-term trends in alcohol consumption and associations with lagged data on specific types of cancer mortality indicated policy implications, and future research and surveillance are needed to investigate, monitor, and quantify the impact of alcohol control policies on trends in cancer mortality.
The association of pattern of lifetime alcohol use and cause of death in the European prospective investigation into cancer and nutrition (EPIC) study.
TLDR
Limiting alcohol use throughout life is associated with a lower risk of death, largely due to cardiovascular disease but also other causes, however, the potential health benefits of alcohol use are difficult to establish.
Alcohol, DNA Methylation, and Cancer
TLDR
Increasing evidence suggests that aberrant patterns of DNA methylation, an important epigenetic mechanism of transcriptional control, also could be part of the pathogenetic mechanisms that lead to alcohol-induced cancer development.
Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada
TLDR
The effect of alcohol of drinking on CRC seems to be modified by obesity, as the risk of CRC increased with drinking years and drinks daily among obese participants, but no increased risk was observed in people without obesity.
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References

SHOWING 1-10 OF 31 REFERENCES
Moderate alcohol intake and cancer incidence in women.
TLDR
Low to moderate alcohol consumption in women increases the risk of certain cancers, and increasing levels of alcohol consumption were associated with a decreased risk of thyroid cancer, non-Hodgkin lymphoma, and renal cell carcinoma.
Alcohol and laryngeal cancer: an update.
TLDR
In various populations, the most commonly used alcoholic beverage appears to be the one most strongly associated with laryngeal cancer risk, suggesting that no meaningful difference exists for different types of alcoholic beverages.
The burden of cancer attributable to alcohol drinking
TLDR
Although the authors' estimates are based on simplified assumptions, the burden of alcohol‐associated cancer appears to be substantial and needs to be considered when making public health recommendations on alcohol drinking.
Alcohol drinking and laryngeal cancer: overall and dose-risk relation--a systematic review and meta-analysis.
Alcohol drinking and colorectal cancer risk: an overall and dose-response meta-analysis of published studies.
TLDR
This meta-analysis provides strong evidence for an association between alcohol drinking of >1 drink/day and colorectal cancer risk.
A meta-analysis of alcohol drinking and cancer risk
TLDR
This meta-analysis showed no evidence of a threshold effect for most alcohol-related neoplasms and the inference is limited by absence of distinction between lifelong abstainers and former drinkers in several studies, and the possible selective inclusion of relevant sites only in cohort studies.
Alcohol consumption and cancers of the oral cavity and pharynx from 1988 to 2009: an update
TLDR
A large body of evidence from epidemiological studies of different designs and conducted in different populations has consistently supported the fact that alcohol consumption is strongly associated with an increase in the risk of oral and pharyngeal cancers.
Alcohol consumption and pancreatic cancer: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4).
TLDR
This collaborative-pooled analysis provides additional evidence for a positive association between heavy alcohol consumption and the risk of pancreatic cancer.
Alcohol drinking and esophageal squamous cell carcinoma with focus on light‐drinkers and never‐smokers: A systematic review and meta‐analysis
TLDR
A systematic review and meta‐analysis further corroborates the association of moderate and high alcohol intake with risk of ESCC and provides risk estimates based on multiple prospective studies.
Alcohol and tobacco use, and cancer risk for upper aerodigestive tract and liver.
TLDR
Alcohol and tobacco consumption are also causally related to liver cancer, although the associations are moderate and a lower fraction of neoplasms is attributable to these factors as compared with cancers of the upper aerodigestive tract.
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