Alcohol‐thiamine interactions: an update on the pathogenesis of Wernicke encephalopathy

@article{Todd1999AlcoholthiamineIA,
  title={Alcohol‐thiamine interactions: an update on the pathogenesis of Wernicke encephalopathy},
  author={K. Todd and A. Hazell and R. Butterworth},
  journal={Addiction Biology},
  year={1999},
  volume={4}
}
Wernicke encephalopathy is a neurological disorder commonly observed in chronic alcohol abuse, in patients with AIDS, and in other conditions of compromised nutritional status. The underlying cause of the disorder is thiamine deficiency. The present review highlights data focusing on alcohol‐thiamine interactions and their relationship to the pathogenesis of Wernicke encephalopathy. Recent findings on the effects of alcohol on thiamine absorption and storage and on thiamine phosphorylation to… Expand
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