Alcaftadine: a topical antihistamine for use in allergic conjunctivitis.

  title={Alcaftadine: a topical antihistamine for use in allergic conjunctivitis.},
  author={R. Namdar and C. Valdez},
  journal={Drugs of today},
  volume={47 12},
  • R. Namdar, C. Valdez
  • Published 2011
  • Medicine
  • Drugs of today
  • Alcaftadine (Lastacaft®; Allergen, Inc.) is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. It also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects. The authors reviewed all available English-language literature characterizing the efficacy, safety and pharmacokinetic profile of alcaftadine ophthalmic solution. In the studies reviewed, alcaftadine was more effective than… CONTINUE READING
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