Albumin stimulates uptake of calcium into subcellular stores in rat cortical astrocytes.

@article{Nadal1996AlbuminSU,
  title={Albumin stimulates uptake of calcium into subcellular stores in rat cortical astrocytes.},
  author={Angel Nadal and Esther Fuentes and Peter A McNaughton},
  journal={The Journal of physiology},
  year={1996},
  volume={492 ( Pt 3)},
  pages={737-50}
}
1. When albumin from either plasma or serum is applied at low concentrations to cortical astrocytes a decrease in the level of [Ca2+]i is observed. At higher concentrations trains of calcium spikes are seen. 2. Removal of the polar lipids which are normally bound to native albumin abolishes the ability to induce spikes, but the decrease in [Ca2+]i is unaffected. The decrease is abolished by the denaturation of albumin and is not reproduced by a number of other proteins, and is therefore a… CONTINUE READING

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