Albumin prevents reactive oxygen species-induced mitochondrial damage, autophagy, and apoptosis during serum starvation


Aberrant levels of reactive oxygen species (ROS) rapidly generated from NADPH oxidase (NOX) activation can be cytotoxic due to activating pro-apoptotic signals. However, ROS also induce pro-survival autophagy through the engulfment of damaged mitochondria. This study is aimed at investigating the cytoprotective role of albumin against NOX/ROS-induced… (More)
DOI: 10.1007/s10495-012-0758-6


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