Albumin helps mediate removal of taurocholate by rat liver.

@article{Forker1981AlbuminHM,
  title={Albumin helps mediate removal of taurocholate by rat liver.},
  author={E. L. Forker and B. Luxon},
  journal={The Journal of clinical investigation},
  year={1981},
  volume={67 5},
  pages={
          1517-22
        }
}
Perfused rat liver removes 97% of the taurocholate from the afferent circulation when the perfusate albumin concentration is 0.5 g/dl. Increasing the albumin concentration 10-fold reduces the concentration of free taurocholate by a factor of five but produces only a 50% reduction in the apparent uptake coefficient. A similar discrepancy is evident from a model-independent analysis of the extraction fractions. From these observations we argue that uptake is not driven solely, or even… Expand
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