Albumin dialysis in critically ill patients: use versus omission of intradialytic heparin.

@article{Yang2008AlbuminDI,
  title={Albumin dialysis in critically ill patients: use versus omission of intradialytic heparin.},
  author={Wen Shin Yang and Han Khim Tan and Hock Foong Lui and Pierce K. H. Chow and Hui Lin Lina Choong and Kok Wong},
  journal={Artificial organs},
  year={2008},
  volume={32 5},
  pages={411-6}
}
Albumin liver dialysis using the Molecular Adsorbent Recirculating System (MARS) (Teraklin AG, Rostock, Germany) is used in severe acute liver failure (ALF). We hypothesized that intradialytic heparin worsens preexisting hemostatic defects without enhancing system longevity or therapeutic efficacy. This was a retrospective, single center study of 10 critically ill patients (M : F = 8:2; mean age 58.5 +/- 16.5 years old; Acute Physiology and Chronic Health Evaluation II 25.0 +/- 3.5) treated… CONTINUE READING

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The use of low dose , intradialytic heparin during MARS exacerbates preexisting severe coagulopathy and thrombocytopenia in patients with severe ALF without enhancing circuit function and longevity .
The use of low dose , intradialytic heparin during MARS exacerbates preexisting severe coagulopathy and thrombocytopenia in patients with severe ALF without enhancing circuit function and longevity .
heparinContraindicated with diseaseThrombocytopenia
The use of low dose , intradialytic heparin during MARS exacerbates preexisting severe coagulopathy and thrombocytopenia in patients with severe ALF without enhancing circuit function and longevity .
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