Albumin dialysis: a new therapeutic strategy for intoxication from protein-bound drugs

@article{Sen2003AlbuminDA,
  title={Albumin dialysis: a new therapeutic strategy for intoxication from protein-bound drugs},
  author={Sambit Sen and Lars M Ytreb{\o} and Christopher F. Rose and Ole-Martin Fuskevaag and Nathan A. Davies and Geir Ivar Nedredal and Roger Williams and A. Revhaug and Rajiv Jalan},
  journal={Intensive Care Medicine},
  year={2003},
  volume={30},
  pages={496-501}
}
ObjectiveAlthough water-soluble drugs can be removed by haemofiltration/haemodialysis, morbidity and mortality from intoxication with protein-bound drugs remains high. The present study investigates whether albumin dialysis in the form of the Molecular Adsorbents Recirculating System (MARS) is effective in removal of protein-bound drugs.DesignProspective animal study.SettingSurgical research laboratory in a university hospital.SubjectsSeven female Norwegian Landrace pigs.InterventionWe studied… 
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