Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase.


Myosin light chain kinase (MLCK) plays an important role in the reorganization of the cytoskeleton, leading to disruption of vascular barrier integrity in multiple organs, including the blood-brain barrier (BBB), after traumatic brain injury (TBI). MLCK has been linked to transforming growth factor (TGF) and rho kinase signaling pathways, but the mechanisms… (More)
DOI: 10.1002/jnr.22600


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