Albert C. Broders' paradigm shifts involving the prognostication and definition of cancer.

@article{Wright2012AlbertCB,
  title={Albert C. Broders' paradigm shifts involving the prognostication and definition of cancer.},
  author={James R. Wright},
  journal={Archives of pathology \& laboratory medicine},
  year={2012},
  volume={136 11},
  pages={
          1437-46
        }
}
  • James R. Wright
  • Published 30 October 2012
  • Medicine
  • Archives of pathology & laboratory medicine
CONTEXT In the 19th and early 20th centuries, cancer was defined by the demonstration of invasion and metastases, based upon gross findings at surgery or autopsy. Although histopathologic examination of tumors became possible with greater and greater resolution over time, the definition of cancer remained the same. Tumors with features suggesting the biological "potential" to invade and metastasize were not cancers until they had achieved their potential. Prognostication based upon… 

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