Akt signals upstream of L-type calcium channels to optimize insulin secretion.

@article{Cui2012AktSU,
  title={Akt signals upstream of L-type calcium channels to optimize insulin secretion.},
  author={Xiuli Cui and Guang Yang and Minglin Pan and Xiao-nan Zhang and S N Yang},
  journal={Pancreas},
  year={2012},
  volume={41 1},
  pages={15-21}
}
OBJECTIVES Both the serine/threonine protein kinase Akt and the voltage-gated L-type calcium channel act as important players in glucose-stimulated insulin secretion. Akt recruits the L-type calcium channel to and maintains them in the plasma membrane. This study aimed to characterize the role of L-type calcium channels in mediation of Akt signaling in… CONTINUE READING