Akt phosphorylates and regulates the function of Dlx5.

  title={Akt phosphorylates and regulates the function of Dlx5.},
  author={Hyung Min Jeong and Y Jin and Yeon-Jin Kim and Jinah Yum and You Hee Choi and C. S. Yeo and Kwang Youl Lee},
  journal={Biochemical and biophysical research communications},
  volume={409 4},
Akt, a phosphoinositide-dependent serine/threonine protein kinase, acts as a key regulator in bone formation. Akt can be activated by several osteogenic signaling molecules, but its precise function and downstream targets in bone development are unknown. Dlx5 transcription factor plays important roles during bone development and osteoblast differentiation… CONTINUE READING