Akathisia: prevalence and risk factors in a community-dwelling sample of patients with schizophrenia. Results from the FACE-SZ dataset

@article{Berna2015AkathisiaPA,
  title={Akathisia: prevalence and risk factors in a community-dwelling sample of patients with schizophrenia. Results from the FACE-SZ dataset},
  author={Fabrice Berna and David Misdrahi and Laurent Boyer and Bruno Aouizerate and Lore Brunel and Delphine Capdevielle and Isabelle Ch{\'e}reau and J. M. Danion and Jean-Michel Dorey and Caroline Dubertret and Julien Dubreucq and Catherine Faget and Franck Gabayet and Christophe Lançon and Jasmina Mallet and Romain Rey and Christine Passerieux and Aur{\'e}lie Schandrin and Franck Schurhoff and Anne Marie Tronche and Mathieu Urbach and P. Vidailhet and Pierre Michel Llorca and Guillaume Fond and Olivier Blanc and Ewa Bulzacka and Isabelle Ch{\'e}reau-Boudet and Gabrielle Chesnoy-Servanin and Thierry d'Amato and A. Deloge and C Delorme and H{\'e}l{\`e}ne Denizot and Maxime Pradier and C. Fluttaz and Sandrine Fonteneau and Elisabeth Giraud-Baro and M.-C. Hardy-Bayle and D. Lacelle and Christophe Lançon and Hakim Laouamri and Marion Leboyer and T. Le Gloahec and Yann Le Strat and Emeline Metairie and Isabelle Offerlin-Meyer and Pauline P{\'e}ri and Sylvie Pires and C{\'e}line Portalier and C. Roman and M. Sebilleau and Arnaud Tessier and Florence Vaillant and Aur{\'e}lie Vehier and Jeanne Vilain and {\`E}lia Vila and Hanan Yazbek and Anna Zinetti-Bertschy},
  journal={Schizophrenia Research},
  year={2015},
  volume={169},
  pages={255-261}
}
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41 Citations
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41 Citations

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Akathisia Among Patients Undergoing Antipsychotic Therapy: Prevalence, Associated Factors, and Psychiatric Impact.
TLDR
Despite the high psychiatric and social burden of akathisia, it remains largely underdiagnosed and undertreated, because in part of its subjective component.
Incidence and risk factors of acute akathisia in 493 individuals with first episode non-affective psychosis: a 6-week randomised study of antipsychotic treatment
TLDR
Among second generation antipsychotics, only olanzapine and quetiapine should be considered as akathisia-sparing drugs, and the type of antipsychotic, having been hospitalized, and a more severe symptomatology at intake seem to predict the development of acute akath isia.
The Role of Antypsychotic Therapy in the Development of Akathisia in Patients with Schizophrenia
TLDR
It was shown that the choice of antipsychotic therapy should be based not only on the actual mental state of the patient, but also considering the potential risk of akathisia.
The Role of Antypsychotic Therapy in the Development of Akathisia in Patients with Schizophrenia
TLDR
It is confirmed that the BARS-MedCalc deal is in fact a takeover of the MedCalc Group, the largest privately-owned company in the world, by a Chinese company.
Роль антипсихотической терапии в развитии акатизии у больных шизофренией
TLDR
It was shown that the choice of antipsychotic therapy should be based not only on the actual mental state of the patient, but also considering the potential risk of akathisia.
Extrapyramidal side effects of antipsychotics: prevalence and risk factors. Results from the national FACE-SZ cohort Cover title Extrapyramidal side effects and antipsychotics
TLDR
The results indicate the high prevalence of EPS in a non-selected community-dwelling clinically stable sample of outpatients with schizophrenia, and monotherapy with an SGA should be preferentially initiated for patients with these sides-effects.
Cigarette smoking and schizophrenia: a specific clinical and therapeutic profile? Results from the FACE-Schizophrenia cohort
Hypovitaminosis D is associated with depression and anxiety in schizophrenia: Results from the national FACE-SZ cohort.
Medication-Induced Akathisia with Newly Approved Antipsychotics in Patients with a Severe Mental Illness: A Systematic Review and Meta-Analysis
TLDR
A systematic review and meta-analysis of akathisia incidence rates of the NAPs, as monotherapy or adjunctive treatment, in adult patients with a severe mental illness, using data from published and unpublished randomized controlled trials to assess the role of study characteristics.
Recommendations of the schizophrenia expert center network for the screening prevention and treatment of sleep disorders based on the results from the real-world schizophrenia FACE-SZ national cohort
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References

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Akathisia: Prevalence and Associated Dysphoria in an In-patient Population with Chronic Schizophrenia
TLDR
The findings support the suggestion that dysphoric mood is an important feature of akathisia, and no significant relation was found between chronic akATHisia and tardive dyskinesia, although there was a trend for trunk and limb dyskine to be commonest in patients with chronic akath isia.
The epidemiology of drug-induced akathisia: Part II. Chronic, tardive, and withdrawal akathisias.
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TLDR
The studies suggest that a significant proportion of patients chronically treated with neuroleptics suffer from akathisia, and the prevalence may be as high as 40 percent, although a conservative estimate would be closer to 30 percent.
Evaluation of akathisia in patients with schizophrenia, schizoaffective disorder, or bipolar I disorder: a post hoc analysis of pooled data from short- and long-term aripiprazole trials
TLDR
Akathisia with aripiprazole occurred early in treatment, was mild-to-moderate in severity, led to few study discontinuations, and did not compromise therapeutic efficacy.
Characteristics and clinical correlates of restless legs syndrome in schizophrenia
On the relationship of atypical and low-dose conventional antipsychotics with akathisia in a clinical patient population
TLDR
The results suggest favouring atypical antipsychotic medication in patients who may easily develop akathisia, although the chlorpromazine equivalent doses of conventional antipsychotics were lower than those of the atypicals.
Variables associated with disparities in treatment of patients with schizophrenia and comorbid mood and anxiety disorders.
TLDR
African Americans were significantly less likely than Caucasians to report having a past or current diagnosis of depression, manic-depression, or anxiety disorder and to be receiving current treatment for these disorders.
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TLDR
The discrepancy between the standard identification methods for neuroleptic-induced movement disorder and the prevalence rate for parkinsonism was much lower per DSM-IV criteria than according to rating scale score.
Trends in the pharmacological treatment of patients with schizophrenia over a 12 year observation period
Managing Antipsychotic-Induced Acute and Chronic Akathisia
TLDR
Based on the available literature, propranolol or other lipophilic β-blockers seem to be the most consistently effective treatment for acute akathisia and addition of benzodiazepines would appear to be a sensible next choice, especially if subjective distress persists.
Acculturation is associated with the prevalence of tardive dyskinesia and akathisia in community‐treated patients with schizophrenia
TLDR
Ethnicity is a risk factor for tardive dyskinesia (TD) and other antipsychotic drug‐induced movement disorders (ADIMD) and this pilot study aimed to explore this interaction by determining if acculturation in migrant groups contributed to the prevalence of ADIMD.
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