Airway wall liquid. Sources and role as an amplifier of bronchoconstriction.

  title={Airway wall liquid. Sources and role as an amplifier of bronchoconstriction.},
  author={Dorne R. Yager and Roger D Kamm and Jeffrey M Drazen},
  volume={107 3 Suppl},
Airway liquid balance in asthma is largely determined by active plasma exudation from tracheobronchial microvessels into the interstitial spaces of the mucosa, submucosa, and/or adventitia, and from there into the luminal space. This exuded plasma is rich in proteins and cell mediators capable of initiating several events, including activation of sensory neural pathways, plasma protein cleavage, inflammatory cell recruitment, and inhibition of surfactant function. It can act to amplify the… CONTINUE READING

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