Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling.

Abstract

Asthma is an obstructive airway disease, with a heterogeneous and multifactorial pathogenesis. Although generally considered to be a disease principally driven by chronic inflammation, it is becoming increasingly recognised that the immune component of the pathology poorly correlates with the clinical symptoms of asthma, thus highlighting a potentially… (More)
DOI: 10.1016/j.pupt.2014.07.005

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