Airway smooth muscle contraction at birth: in vivo versus in vitro comparisons to the adult.

@article{Fisher1992AirwaySM,
  title={Airway smooth muscle contraction at birth: in vivo versus in vitro comparisons to the adult.},
  author={John Timothy Fisher},
  journal={Canadian journal of physiology and pharmacology},
  year={1992},
  volume={70 4},
  pages={590-6}
}
It is clear from the literature that considerable postnatal development occurs in the contractile properties of skeletal and cardiac muscle. Nevertheless, few studies have focused on developmental changes in airway smooth muscle or on the functional capabilities of airway innervation in the newborn. Conclusions about force generation, based on measurements of pulmonary mechanics during stimulation of the vagus nerves, suggest that the newborn possesses a reduced capability to narrow airway… CONTINUE READING