Airway responsiveness to adenosine 5'-monophosphate and exhaled nitric oxide measurements: predictive value as markers for reducing the dose of inhaled corticosteroids in asthmatic subjects.

@article{Prieto2003AirwayRT,
  title={Airway responsiveness to adenosine 5'-monophosphate and exhaled nitric oxide measurements: predictive value as markers for reducing the dose of inhaled corticosteroids in asthmatic subjects.},
  author={Luis M Prieto and Laura Bruno and V. H. Contreras Guti{\'e}rrez and Sonia Uixera and Carmen P{\'e}rez-Franc{\'e}s and Amparo Lanuza and Ana Ferrer},
  journal={Chest},
  year={2003},
  volume={124 4},
  pages={1325-33}
}
OBJECTIVES To investigate the utility of the determination of airway responsiveness to inhaled adenosine 5'-monophosphate (AMP) and exhaled nitric oxide (ENO) levels as markers for safely reducing the dose of inhaled corticosteroids (ICS) in patients with asthma well controlled with a moderately high ICS dose. METHODS A total of 37 patients with asthma well controlled for at least 3 months by treatment with a moderately high ICS dose (beclomethasone dipropionate, 500 to 1,000 microg or… CONTINUE READING
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