Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology.

@article{Aysola2008AirwayRM,
  title={Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology.},
  author={Ravi S. Aysola and Eric A. Hoffman and David S. Gierada and Sally W Wenzel and Janice Cook-Granroth and Jaime Tarsi and Jie Zheng and Kenneth B. Schechtman and Thiruvamoor P Ramkumar and Rebecca B Cochran and E Xueping and Chandrika Christie and John W. Newell and Sean E Fain and Talissa A. Altes and Mario Castro},
  journal={Chest},
  year={2008},
  volume={134 6},
  pages={
          1183-1191
        }
}
BACKGROUND To prospectively apply an automated, quantitative three-dimensional approach to imaging and airway analysis to assess airway remodeling in asthma patients. METHODS Using quantitative software (Pulmonary Workstation, version 0.139; VIDA Diagnostics; Iowa City, IA) that enables quantitative airway segment measurements of low-dose, thin-section (0.625 to 1.25 mm), multidetector-row CT (MDCT) scans, we compared airway wall thickness (WT) and wall area (WA) in 123 subjects participating… CONTINUE READING