Airway remodeling in asthma.

@article{Vignola2003AirwayRI,
  title={Airway remodeling in asthma.},
  author={Antonio Maurizio Vignola and Franco Mirabella and Giorgio Costanzo and Rossana Di Giorgi and Mark Gjomarkaj and Vincenzo Bellia and Giovanni Bonsignore},
  journal={Chest},
  year={2003},
  volume={123 3 Suppl},
  pages={417S-22S}
}
Chronic inflammation and remodeling may follow acute inflammation or may begin insidiously as a low-grade smoldering response, especially in the case of immune reactions. The histologic hallmarks of chronic inflammation and remodeling are as follows: (1) infiltration by macrophages and lymphocytes; (2) proliferation of fibroblasts that may take the form of myofibroblasts; (3) angiogenesis; (4) increased connective tissue (fibrosis); and (5) tissue destruction. It is clear that changes in the… CONTINUE READING

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