Airway pressure release ventilation prevents ventilator-induced lung injury in normal lungs.

Abstract

IMPORTANCE Up to 25% of patients with normal lungs develop acute lung injury (ALI) secondary to mechanical ventilation, with 60% to 80% progressing to acute respiratory distress syndrome (ARDS). Once established, ARDS is treated with mechanical ventilation that can paradoxically elevate mortality. A ventilation strategy that reduces the incidence of ARDS… (More)
DOI: 10.1001/jamasurg.2013.3746

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