Airway nitric oxide in patients with cystic fibrosis is associated with pancreatic function, Pseudomonas infection, and polyunsaturated fatty acids.

@article{Keen2007AirwayNO,
  title={Airway nitric oxide in patients with cystic fibrosis is associated with pancreatic function, Pseudomonas infection, and polyunsaturated fatty acids.},
  author={C. Keen and A. Olin and Asa Edentoft and E. Gronowitz and B. Strandvik},
  journal={Chest},
  year={2007},
  volume={131 6},
  pages={
          1857-64
        }
}
BACKGROUND Airway nitric oxide (NO) is low or normal in cystic fibrosis (CF) patients. This may affect bacterial status since NO has antimicrobial properties. Arachidonic acid (AA), which is increased in the serum and airways of CF patients, has been shown to reduce NO levels. The aim of this study was to investigate whether airway NO level correlates with genotype and pancreatic function, and whether low airway NO level is associated with bacterial infection and increased serum AA level in CF… Expand
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