Airway modeling and remodeling in the pathogenesis of asthma.

  title={Airway modeling and remodeling in the pathogenesis of asthma.},
  author={Stephanie Mary Warner and Darryl A Knight},
  journal={Current opinion in allergy and clinical immunology},
  volume={8 1},
PURPOSE OF REVIEW Asthma remains a severe health problem since current therapies are directed to suppressing, rather than preventing or reversing, the primary disease process. Clearly, a greater understanding of the pathogenesis of asthma is critical to the development of better therapeutic modalities. In this review, we discuss the recent advancements in research targeting the role of airway remodeling in asthma. RECENT FINDINGS Epithelial fragility and abnormalities are being recognized as… CONTINUE READING