Airway inflammation in mild intermittent and in persistent asthma.
@article{Vignola1998AirwayII,
title={Airway inflammation in mild intermittent and in persistent asthma.},
author={Antonio Maurizio Vignola and Pascal Chanez and Alison M. Campbell and Françoise Souques and B. Lebel and Ingrid Enander and Jean Bousquet},
journal={American journal of respiratory and critical care medicine},
year={1998},
volume={157 2},
pages={
403-9
}
}The severity of asthma can be graded from mild intermittent to severe persistent. Airway inflammation is a feature of persistent asthma. We compared several markers of inflammation in mucosal biopsies and bronchoalveolar lavage fluid (BAL fluid) from 12 healthy control subjects, 24 patients with intermittent asthma, and 18 patients with mild-to-moderate persistent asthma. Epithelial shedding, eosinophil (EG2-positive cells), and activated T-cell (UCHL1) counts in biopsies, and ECP levels in BAL…
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