Airway inflammation and functional changes after exposure to different concentrations of isocyanates.

@article{Lemiere2002AirwayIA,
  title={Airway inflammation and functional changes after exposure to different concentrations of isocyanates.},
  author={Catherine Lemiere and Philippe Rom{\'e}o and Simone Chaboillez and Caroline Tremblay and J P Malo},
  journal={The Journal of allergy and clinical immunology},
  year={2002},
  volume={110 4},
  pages={641-6}
}
BACKGROUND Isocyanates are a common cause of occupational asthma (OA). OBJECTIVES We sought (1) to examine whether asthmatic reactions to isocyanates could be induced at concentrations as low as 1 ppb in subjects with OA caused by isocyanates previously diagnosed in our center and (2) to compare the inflammatory and functional changes after exposure to 1 and 15 ppb of isocyanates with similar total doses (concentration of isocyanates x duration of exposure). METHODS Specific inhalation… CONTINUE READING

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