Airway hyperresponsiveness and calcium handling by smooth muscle: a "deeper look".

@article{Parameswaran2002AirwayHA,
  title={Airway hyperresponsiveness and calcium handling by smooth muscle: a "deeper look".},
  author={Krishnan Parameswaran and Luke Jeffrey Janssen and Paul M O'Byrne},
  journal={Chest},
  year={2002},
  volume={121 2},
  pages={621-4}
}
We propose that abnormal calcium handling by the airway smooth muscle may be an important determinant of airway hyperresponsiveness. The amplitude, frequency, or localization of Ca(2+) oscillations in the smooth muscle may determine the degree of airway sensitivity and reactivity, which are characteristic features of asthma. 

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