Airway fungal colonization compromises the immune system allowing bacterial pneumonia to prevail.

@article{Roux2013AirwayFC,
  title={Airway fungal colonization compromises the immune system allowing bacterial pneumonia to prevail.},
  author={Damien Roux and St{\'e}phane Gaudry and Linda Khoy-Ear and Meryem Aloulou and Mathilde Phillips-Houlbracq and Julie Bex and David Skurnik and Erick Denamur and Renato C Monteiro and Didier Dreyfuss and J L Ricard},
  journal={Critical care medicine},
  year={2013},
  volume={41 9},
  pages={e191-9}
}
OBJECTIVE To study the correlation between fungal colonization and bacterial pneumonia and to test the effect of antifungal treatments on the development of bacterial pneumonia in colonized rats. DESIGN Experimental animal investigation. SETTING University research laboratory. SUBJECTS Pathogen-free male Wistar rats weighing 250-275 g. INTERVENTIONS Rats were colonized by intratracheal instillation of Candida albicans. Fungal clearance from the lungs and immune response were measured… CONTINUE READING

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Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.

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