Airway function correlates with circulating eosinophil, but not mast cell, markers of inflammation in childhood asthma.

@article{Rao1996AirwayFC,
  title={Airway function correlates with circulating eosinophil, but not mast cell, markers of inflammation in childhood asthma.},
  author={Raghavendra Rao and James Frederick and Ingrid Enander and Rachael Kathleen Gregson and Jane A Warner and John O. Warner},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={1996},
  volume={26 7},
  pages={789-93}
}
BACKGROUND Lung function tests, including forced expiratory volume in one second (FEV1), forced expiratory flow at 25-75% of vital capacity (FEF25-75%) and provocation concentrations of histamine which reduce FEV1 by 20% (PC20), are used as indicators of airway form and function in bronchial asthma. Recently, markers of eosinophil activation in bronchial lavage and serum have been suggested as a measure of eosinophil mediated inflammation in the airways. These include eosinophil cationic… CONTINUE READING