Airway epithelial cells--hyperabsorption in CF?

@article{Kunzelmann2012AirwayEC,
  title={Airway epithelial cells--hyperabsorption in CF?},
  author={Karl Kunzelmann and Rainer Schreiber},
  journal={The international journal of biochemistry & cell biology},
  year={2012},
  volume={44 8},
  pages={1232-5}
}
Airway epithelial cells transport electrolytes and are central to the disease cystic fibrosis (CF), which is an inherited transport defect affecting smaller airways and a number of other epithelial organs. Clinically, CF is dominated by a chronic lung disease, the main cause of morbidity and mortality. Airway obstruction by thick mucus and chronic infection by Pseudomonas aeruginosa eventually lead to loss of pulmonary function. Loss of function of CFTR Cl(-) channels was found to be the cause… CONTINUE READING

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