Airway beta-adrenoceptor number in cystic fibrosis and asthma.

  title={Airway beta-adrenoceptor number in cystic fibrosis and asthma.},
  author={Rakhi Sharma and Peter Key Jeffery},
  journal={Clinical science},
  volume={78 4},
1. Maximal binding capacity (Bmax) and the dissociation constant (KD) for the beta-adrenoceptor antagonist 125I-cyanopindol were estimated in membrane preparations of hilar, lobar/main bronchi (level I) and peripheral lung (level II) of grossly normal lungs resected for bronchial carcinoma. The tissue distribution of 125I-cyanopindol-binding sites was assessed by autoradiography of complementary cryostat sections. The data obtained from the resections for carcinoma and bronchiectasis were used… CONTINUE READING

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