Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.

@article{Rock2010AirwayBS,
  title={Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.},
  author={Jason R Rock and Scott H. Randell and Brigid L M Hogan},
  journal={Disease models & mechanisms},
  year={2010},
  volume={3 9-10},
  pages={
          545-56
        }
}
The small airways of the human lung undergo pathological changes in pulmonary disorders, such as chronic obstructive pulmonary disease (COPD), asthma, bronchiolitis obliterans and cystic fibrosis. These clinical problems impose huge personal and societal healthcare burdens. The changes, termed 'pathological airway remodeling', affect the epithelium, the underlying mesenchyme and the reciprocal trophic interactions that occur between these tissues. Most of the normal human airway is lined by a… CONTINUE READING
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