Airway and systemic effects of hydrofluoroalkane formulations of high-dose ciclesonide and fluticasone in moderate persistent asthma.

@article{Lee2005AirwayAS,
  title={Airway and systemic effects of hydrofluoroalkane formulations of high-dose ciclesonide and fluticasone in moderate persistent asthma.},
  author={Daniel C. Lee and Thomas C. Fardon and Caroline E. Bates and Kay Haggart and Lesley C. McFarlane and Brian J Lipworth},
  journal={Chest},
  year={2005},
  volume={127 3},
  pages={
          851-60
        }
}
BACKGROUND There are no data comparing the relative effects of high-dose ciclesonide (CIC) and fluticasone propionate (FP) on airway and systemic outcomes in patients with moderate persistent asthma. OBJECTIVE We elected to evaluate the relative effects of CIC and FP on the plasma cortisol response to stimulation with human corticotropin-releasing factor (hCRF) and bronchial hyperresponsiveness to methacholine as the primary outcome variables, in addition to secondary outcomes of overnight 10… CONTINUE READING
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