Airway IFN-γ Production During RSV Bronchiolitis is Associated with Eosinophilic Inflammation

@article{Kim2011AirwayIP,
  title={Airway IFN-γ Production During RSV Bronchiolitis is Associated with Eosinophilic Inflammation},
  author={Chang Keun Kim and Zak Callaway and Young Yull Koh and Soo-Hee Kim and Takao Fujisawa},
  journal={Lung},
  year={2011},
  volume={190},
  pages={183-188}
}
This study was designed to investigate the possible role of IFN-γ in eosinophil degranulation that occurs during respiratory syncytial virus (RSV) bronchiolitis. Sixty-seven infants, 2–24 months old and hospitalized with their first episode of acute RSV bronchiolitis, were selected for this study. Eosinophil-active cytokine and chemokine profiles in nasal lavage supernatants taken within the first 48 h of admission were determined by a multiplex bead array system (Luminex). Comparisons were… CONTINUE READING
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