Airway Biofilms

@article{Kobayashi2005AirwayB,
  title={Airway Biofilms},
  author={Hiroyuki Kobayashi},
  journal={Treatments in Respiratory Medicine},
  year={2005},
  volume={4},
  pages={241-253}
}
The differentiation of bacterial biofilms in the airway environment, the pathogenesis of airway biofilm, and possible therapeutic methods are discussed. Biofilm diseases that characteristically involve the respiratory system include cystic fibrosis (CF), diffuse panbronchiolitis (DPB), and bronchiectasia with Pseudomonas aeruginosa (P. aeruginosa) infection. There is evidence to suggest that almost all strains of P. aeruginosa have the genetic capacity to synthesize alginate, a main matrix of… Expand
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21 Citations
Background Citations
3
Methods Citations
1

21 Citations

Citation Type

Citation Type

Fungi in the cystic fibrosis lung: bystanders or pathogens?
TLDR
The prevalence and importance of fungi in the CF airway has likely been underestimated with the most frequently isolated filamentous fungi being Aspergillus fumigatus and Scedosporium apiospermum and the major yeast Candida albicans. Expand
Potential role of biofilms in deep cervical abscess.
TLDR
Initial evidence suggests that biofilm phenotypes could play a role in the pathogenesis and recalcitrance of deep neck infections, particularly in larger abscesses. Expand
Microbial biofilm: A matter of grave concern for human health and food industry
TLDR
This review discusses the colonization of pathogenic microorganisms on tissues and medically implanted devices in human beings, and focuses on food spoilage, disease outbreaks, biofilm‐associated deaths, burden on economy, and other major concerns ofBiofilm‐forming pathogenicmicroorganisms in food industries like dairy, poultry, ready‐to‐eat food, meat, and aquaculture. Expand
Neutrophilic inflammation as a major determinant in the progression of cystic fibrosis.
TLDR
It is argued that the current paradigm that views neutrophils as short-lived indiscriminate killers is seriously flawed and researchers and clinicians need to view the pathophysiological importance of neutrophil importance in a new light, to the ultimate benefit of patients. Expand
Update on treatment of pulmonary exacerbations in cystic fibrosis
  • A. Smyth
  • Medicine
  • Current opinion in pulmonary medicine
  • 2006
TLDR
Pulmonary exacerbations in cystic fibrosis are defined and their importance in the pathophysiology and progression of this condition is explained and the importance of prevention and prompt treatment is stressed. Expand
Biofilms of Lactobacillus plantarum and Lactobacillus fermentum: Effect on stress responses, antagonistic effects on pathogen growth and immunomodulatory properties.
TLDR
The biofilm mode of life is associated with beneficial probiotic properties of lactobacilli, in a strain dependent manner, and characterization of isolate phenotype in the biofilm state could be additional valuable information for the selection of probiotic strains. Expand
Source Control and Supporting Therapeutics: Integrating Bacterial Invasion, Host Defense, and Clinical Interventions with Source Control Procedures
TLDR
This chapter will address how one may integrate standard source control practices with recent data on potentially controllable elements that may enable host defense success. Expand
Revealing the dynamics of polymicrobial infections: implications for antibiotic therapy.
As a new generation of culture-independent analytical strategies emerge, the amount of data on polymicrobial infections will increase dramatically. For these data to inform clinical thinking, and in… Expand
Treatment of pulmonary exacerbations in cystic fibrosis
TLDR
Although there is no universal definition of a pulmonary exacerbation in cystic fibrosis, proposed definitions have many similarities and the current recommendations for treatment of pulmonary exacerbations, including the duration and location of treatments are outlined. Expand
Dynamic removal of oral biofilms by bubbles.
TLDR
A mathematical model of the removal process was proposed and was able to simulate the kinetics of the biofilm removal process and the fraction of biofilm removed per bubble collision is much larger than would have been expected based on previous research employing bubbles that moved slowly along a surface that was partially covered with adherent bacteria. Expand
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