Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients.

Abstract

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED, or APS1), is a monogenic autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene. The three main components of APECED are chronic mucocuteaneous candidiasis, hypoparathyroidism and adrenocortical insufficiency. However, several additional endocrine or other… (More)

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Cite this paper

@article{Pntynen2006AireDM, title={Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients.}, author={Nora P{\"o}ntynen and Aaro Miettinen and T. Petteri Arstila and Olle K{\"a}mpe and Mohammad Alimohammadi and Outi Vaarala and Leena Peltonen and Ismo Ulmanen}, journal={Journal of autoimmunity}, year={2006}, volume={27 2}, pages={96-104} }