Airborne Seafood Allergens as a Cause of Occupational Allergy and Asthma

@article{Lopata2013AirborneSA,
  title={Airborne Seafood Allergens as a Cause of Occupational Allergy and Asthma},
  author={A. L. Lopata and Mohamed Fareed Jeebhay},
  journal={Current Allergy and Asthma Reports},
  year={2013},
  volume={13},
  pages={288-297}
}
Occupational allergy and asthma is a serious adverse health outcome affecting seafood-processing workers. Allergic reactions are directed to two major seafood groups: fish and shellfish, with the latter group comprising crustaceans and molluscs. Several allergenic proteins have been identified in these different groups, but few have been characterised on a molecular level. Parvalbumin appears to be the major fish allergen, while tropomyosin the major crustacean allergen. Other IgE-binding… 
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References

SHOWING 1-10 OF 57 REFERENCES
Occupational seafood allergy: a review
TLDR
The range of allergic disease associated with occupational exposure to crab is well characterised, whereas for other seafood agents the evidence is somewhat limited, and there is a need for further epidemiological studies to better characterise this risk.
Seafood workers and respiratory disease: an update
TLDR
Molecular studies of the allergens suggest that aside from tropomyosin and parvalbumin, other as yet uncharacterized allergens are important, which needs to be considered in order to standardize exposure assessment techniques, which are key to assessing the impact of interventions.
IgE-mediated sensitization in seafood processing workers.
TLDR
Investigation of the prevalence, work-related symptoms, and possible risk factors in this occupationally exposed population of fish and seafood processing workers in Greece found presence of atopy, intensity, and duration of exposure was found as potential risk factors for IgE sensitization.
Occupational allergy and asthma in the seafood industry – emerging issues
TLDR
This overview of occupational allergies and asthma in seafood exposed workers illustrates the changing nature of the fishing and seafood processing industry in the midst of ecological degradation and globalisation.
New insights into seafood allergy
TLDR
Molecular characterization of more universal marker allergens for the three major seafood groups will improve current component-resolved clinical diagnosis and have a significant impact on the management of allergic patients, on food labeling and on future immunotherapy for seafood allergy.
Shellfish allergy
  • A. Lopata, R. O'Hehir, S. Lehrer
  • Biology
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2010
TLDR
Future research on the molecular structure of tropomyosins with a focus on the immunological and particularly clinical cross‐reactivity will improve diagnosis and management of this potentially life‐threatening allergy and is essential for future immunotherapy.
Salmon allergen exposure, occupational asthma, and respiratory symptoms among salmon processing workers.
TLDR
A sensitive method to measure salmon antigen in air was developed and found that filleting workers were most exposed, and it is important to reduce aerosols by improving the ventilation system, machines and organization of work since respiratory symptoms at work among workers were common.
Occupational allergies in seafood-processing workers.
Fish Allergy: In Review
TLDR
This contemporary review discusses interesting and new findings in the area of fish allergy including demographics, novel allergens identified, immunological mechanisms of sensitization, and innovative approaches in diagnosing and managing this life-long disease.
Exposure to the fish parasite Anisakis causes allergic airway hyperreactivity and dermatitis.
...
...