Air pollutants, genes and early childhood acute bronchitis.

  title={Air pollutants, genes and early childhood acute bronchitis.},
  author={R Ghosh and J. Rick Topinka and Jesse P. Joad and Miroslav Dost{\'a}l and Radim J. {\vS}r{\'a}m and Irva Hertz-Picciotto},
  journal={Mutation research},
  volume={749 1-2},
BACKGROUND Studies have reported gene-by-environment interaction for chronic respiratory conditions but none on acute illnesses in children. We investigated, longitudinally, whether genotype modifies the relationship of environmental exposures (second-hand tobacco smoke, polycyclic aromatic hydrocarbons, particulate matter <2.5μm (PM2.5)) with acute bronchitis in children below two years. METHODS A random sample of 1133 children, born between 1994 and 1998, in two districts of the Czech… CONTINUE READING
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